RARγ and Cdx1 Interactions in Vertebral Patterning
نویسندگان
چکیده
منابع مشابه
RARg and Cdx1 Interactions in Vertebral Patterning
Exogenous retinoic acid (RA) can evoke vertebral homeosis when administered during late gastrulation. These vertebral transformations correlate with alterations of the rostral limit of Hox gene expression in the prevertebrae, suggesting that retinoid signaling regulates the combinatorial expression of Hox genes dictating vertebral identity. Conversely, loss of certain RA receptors (RARs) result...
متن کاملCdx1 autoregulation is governed by a novel Cdx1-LEF1 transcription complex.
The Cdx1 gene product is essential for normal anterior-posterior vertebral patterning. Expression of Cdx1 is regulated by several pathways implicated in anterior-posterior patterning events, including retinoid and Wnt signaling. We have previously shown that retinoic acid plays a key role in early stages of Cdx1 expression at embryonic day 7.5 (E7.5), while both Wnt3a signaling and an autoregul...
متن کاملA resegmentation‐shift model for vertebral patterning
Segmentation of the vertebrate body axis is established in the embryo by formation of somites, which give rise to the axial muscles (myotome) and vertebrae (sclerotome). To allow a muscle to attach to two successive vertebrae, the myotome and sclerotome must be repositioned by half a segment with respect to each other. Two main models have been put forward: 'resegmentation' proposes that each h...
متن کاملVertebral and rib anatomy in Caperea marginata: Implications for evolutionary patterning of the mammalian vertebral column
The pygmy right whale, Caperea marginata, is a rare mysticete cetacean with an unusual suite of axial skeletal characters. Distally expanded first ribs, a long thorax with broadly overlapping vertebral transverse processes, plate-like posterior ribs, and a short tail contrast with other cetaceans and suggest unique developmental patterning. Twenty-four individuals of diverse ontogenetic age wer...
متن کاملKinesic Patterning in Deceptive and Truthful Interactions
A persistent question in the deception literature has been the extent to which nonverbal behaviors can reliably distinguish between truth and deception. It has been argued that deception instigates cognitive load and arousal that are betrayed through visible nonverbal indicators. Yet, empirical evidence has often failed to find statistically significant or strong relationships. Given that inter...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Developmental Biology
سال: 2001
ISSN: 0012-1606
DOI: 10.1006/dbio.2001.0455